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Pioneering cardiomyocyte-selective modified mRNA therapeutics designed to regenerate and protect the  injursed heart

Precision mRNA Therapeutics for Cardiac Repair

Targeted Delivery with CM-SMRTs

Our proprietary CM-SMRTs platform selectively enables therapeutic protein expression in cardiomyocytes while minimizing off-target expression

Preclinical studies demonstrate selective expression in cardiomyocytes (red) using CM-SMRTs compared to conventional modRNA delivery

Peer Reviewed Publications

Selective modRNA delivery to cardiac muscle

Large animal model success

Our Mission

Cardiovascular disease remains the leading cause of death worldwide. Current treatments only manage symptoms or restore blood flow, but there are no approved therapies capable of rebuilding damaged myocardium

Our Objective

SeleRNA is developing modRNA therapeutics designed to restore cardiac function by activating repair and regeneration after injury 

Our Approach

Using our CM-SMRTs platform, we aim to selectively and transiently express therapeutic proteins in cardiomyocytes while minimizing off-target effects

Why It Matters

We seek to move treatment beyond supportive care toward true myocardial recovery with regenerative therapeutics designed to improve functional performance

Led by Expert Researchers
world-class experience in cardiac regeneration and modRNA therapeutics

Proud Partner of the Icahn School of Medicine at Mount Sinai

Pioneering the future of cardiac therapy through cardiomyocyte-selective modRNA translation to transform hearts and lives.

2026 SeleRNA. All Rights Reserved. | Advancing Cardiac Therapeutics Through Innovative ModRNA Technology

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